LABORATORY│Kumamoto University Organic Chemistry Nishino's Laboratory

LABORATORY

Hiroshi Nishino, D.Sc.
Professor

《Hobby》

■ Study of the Land Mollusk

■ Photograph of the Wildlife

■ Swimming, Jogging, Softball, Tennis, Skating,
　　Football, Hiking, Caving, and etc.

■ Driving my Kawasaki Vulcan 1500 FI

■ Hearing BGM
　(BT, RS, CCR, GFR, DP, VH, EP, CT, DL, BS,
　 John Fogerty, U2, Eric Clapton,and etc)

Personal History

《Education》

1975-1979

　Department of Chemistry, Faculty of Science, Kumamoto University
Awarded the degree of B.Sc. in chemistry

1979-1981

　Department of Chemistry, Faculty of Science, Kumamoto University
Awarded the degree of M.Sc. in chemistry for a thesis entitled "Oxidation of 9-Xanthenones with Manganese(III) Acetate. Regioselective Carboxylation." Work supervised by Professor Kazu Kurosawa

1988

　Awarded the degree of Ph.D. in chemistry by Department of Chemistry,
Faculty of Science, Tohoku University for a thesis entitled "Study of Organic Reactions Using Manganese(III) Complexes." Work supervised by Professor Kazu Kurosawa and Professor Sho Ito

《Research and Professional Experience》

1981/4-1996/3

　Research Associate at the Department of Chemistry, Faculty of Science,
Kumamoto University, working with Professor Kazu Kurosawa on studying free-radical carbon-carbon bond formation of organic compounds using metal oxidants, catalytic oxidation of unsaturated hydrocarbons using manganese complexes, and photochemical reaction of organic compounds.

1988/3-1989/5

　Overseas Research Personnel of the Ministry of Education, Science and Culture, Japan, at the Department of Chemistry, University of Houston, U.S.A., working with Professor Jay K. Kochi on studying charge-transfer complexes of dioxochromium(VI) salts with organic molecules

1989/6-1990/1

　Postdoctoral Fellow of the Department of Chemistry, Rice University, U.S.A., working with Professor Tohru Fukuyama on studying total synthesis of Porothramycins

1996/3-8
　Overseas Research Personnel of the Ministry of Education, Science, Sports and Culture, Japan,
at the Department of Chemistry, Texas A&M University, working with Professor Derek Harold R. Barton;
at the Department of Chemistry, Ohio State University, working with Professor Leo A. Paquette;
at the Department of Chemistry, Brandeis University, working with Professor Barry B. Snider.

1996/4-1999/6

　Associate Professor at the Department of Chemistry, Faculty of Science, Kumamoto University

1999/7-2000/3

　Professor at the Department of Chemistry, Faculty of Science, Kumamoto University

2000/4-2002/3

　Professor at the Institute for Fundamental Research of Organic Chemistry (IFOC), Kyushu University

2002/4-2004/3

　Professor at the Department of Chemistry, Faculty of Science, Kumamoto University

2004/4-2006/3

　Professor at the Department of Science, Faculty of Science, Kumamoto University

2006/4-Present

　Professor at the Department of Chemistry, Graduate School of Science and Technology, Kumamoto University

2006/4-2008/3

　Education & Research Senator
Vice Dean, Graduate School of Science and Technology, Kumamoto University

2008/4-Present

　Dean, Faculty of Science, Kumamoto University

　
《Awards》

1994/12

Award for Encouragement of Kyushu-Yamaguchi Branches of the Society of Synthetic Organic Chemistry, Japan, on Development of Free-Radical Reactions Using Manganese(III) Complexes

2001

　The Best Poster Presentation Award at the 79th National Meeting of the Chemical Society of Japan, 　Kobe, 　March 　28-31, 　2001, 　entitled 　“Oxidation 　of 2-Hydroxy-2-phenyl-1,2-dihydroacenaphthylen-1-one with Manganese(III) Acetate,” by Shingo Sakai, Hiroshi Nishino, and Kazu Kurosawa, Abstracts II, p1428 (2001).

2005

　The Best Poster Presentation Award at The 17th Japan-Korea Joint Seminar for Young Organic Chemists, Nagasaki, November 12, 2005, entitled "Synthesis of [4.3.3]propellanes Using Mn(III)-Induced Oxidative Cyclization,"Kentaro Asahi and Hiroshi Nishino, Abstracts, p 23 (2005).

STUFF ［2009］

■Number of Stuff in Nishino Laboratory

	UG	M1	M2	D1	D2	D3	RA	Total
2009	7	5	7	1	1	1	1	23
2008	4	7	2	2	1	2	0	18
2007	8	2	8	1	3	0	0	22
2006	5	9	8	3	0	0	0	25
2005	9	8	5	0	0	1	0	23
2004	8	5	6	0	0	1	0	20
2003	7	6	3	0	1	2	1	20
2002	7	3	5	1	2	0	1	19
2001	5	7	6	2	0	0	1	21
2000	6	8	5	0	0	2	0	21

《 Doctor Course Fellow 》


Name	Yosuke Ito (D3)
Theme	Study on the Synthesis of Super Molecular Macrocyclic Compounds Using Manganese(III)-Induced Macrocyclization
Comment	He is deeply absorbed in working his Ph.D. research work and he will take the Ph.D. in next March.


Name	Md. Aminul Haque（D1）
Theme	Study of Manganese(III)-Catalyzed Aerobic Oxidation
Comment	He came from Dhaka University, Bangladesh, at October, 2008. He is a nice guy and a good pappy as well as a hard organic researcher.


Name	Susumu Wakamiya（D1）
Theme	Study on the Intramolecular Tandem Cyclization of 2-Propenyl 2-(2-Oxoethyl)-3-oxobutanoates Using Manganese(III) Acetate
Comment	On the way of job hunting, he is stopping out.


Name	Mehtap Yakut（Guest Scholar Visiting Research Fellow）
Theme	Study of Manganese(III)-Catalyzed Aerobic Oxidation of Coumarin Derivatives
Comment	She came from Department of Chemistry, Graduate School of Natural & Applied Sciences, Ankara University, Turkey at November, 18, 2009. She is a considerate chemist, but a hard organic researcher as well .

《 Master Course Fellow 》


Name	Hikaru Igarashi（M2）
Theme	Study on the Hydroperoxidation of Cyclic 1,3-Dicarbonyl Compounds
Comment	He came from Fukuoka University of Education to join our group at 2008. His favorite is Tamana Japanese Needles (Ramen). He is now working hard for his research to graduate our Department. He is a nice guy for taking care of his junior.


Name	Sayaka Inoue（M2）
Theme	Study on the Selective Synthesis of Dihydroisoquinolinones and Dihydrooxazinones
Comment	She is now fighting her study though she looks slender. she is sure to enjoy her organic chemistry.


Name	Yayoi Onizuka（M2）
Theme	Study on the Manganese(III)-Based Tandem Cyclization of Alkenes with Tetraketones
Comment	Tandem cyclization is a one of the most convenient technique to synthesize heterocyclic compounds. She is now working hard to complete her study.


Name	Tomoyuki Kawakami（M2）
Theme	Study on the Oxidation of Dihydrofurylnaphthalenes with Manganese(III) Acetate
Comment	It is difficult to construct the [6,6,6,5]-membered ring system. He is now thinking of breaking through the problem.


Name	Toshiyuki Kawanabe（M2）
Theme	Study on the Convenient Photo-Induced Transformation of Functionalized Pyrroles into 3H-benz[e]indoles
Comment	The photoreaction is very simple and useful for the synthesis of aromatic heterocycles. He is sure to say that the photocyclization is the best way to prepare the aromatic heterocycles!


Name	Takanori Nagashimada（M2）
Theme	NStudy on the Oxidative Intramolecular Cyclization of Diethyl N-(Arylamino)ethylmalonates
Comment	He is the most tough guy in Nishino Research Group. He has not only a nice skill in organic synthesis, but also a good player in softball game.


Name	Takahiro Hyakutake（M2）
Theme	Study on the Reaction of 1,3-Cycloalkanediones with Metal Oxidants
Comment	His research work is to study a surprised and unique oxidative coupling to give chrysenediones. Recently, he is getting a light of the reaction!


Name	Nobutaka Kikue（M1）
Theme	Study on the New Synthesis of Indolinones Using Intramolecular Radical Cyclization
Comment	He looks like a pooh-bear, but he is a nice guy not only for managing very well in Nishino Research Group, but also of great insight for organic chemistry.


Name	Misako Takahashi (M1)
Theme	Study on the Synthesis of Pyrrolinones from the Reaction of Anilines with 1,3-Dicarbonyl Compounds
Comment	She came from Ryukyu University at 2009. Although she has done the isolation and determination of natural products at Ryukyu University, she is now doing a synthetic organic chemistry. She must need power!


Name	Yuki Hatakeyama (M1)
Theme	Study on the Synthesis of Aminolactones and Amino Acids Using the Capto-Dative Effect
Comment	Her research work looks like simple, but she will never get away with it! It is difficult to read Russian paper. God, help her.


Name	Kazuya Machida（M1）
Theme	Study on the Synthesis of Spiro Compounds from the Intramolecular Cyclization of Curcuminoids
Comment	As you know, one of the best medicine for a hangover is curcumin isolated from Curcuma longa L. However, it is somewhat difficult to synthesize the curcuminids in vitro. He is very impressed the power of the plant.


Name	Yuuki Matsui（M1）
Theme	Study on the Manganese(III)-Based Tandem Cyclization of 4-Pentenyl 3-Oxobutanoates
Comment	The 5-7 ring system is a nice matching ring-fused system. However, it is difficult to synthesize the ring system. Why?

《 Under Graduate Fellow 》


Name	Shota Ishiguro (UG4)
Theme	Study on the Synthesis of Arenes bearing Two Heterocyclic Substituents Using Acylacetonitrile Building Block
Comment	On the way of training for the high school teacher.


Name	Miyuki Omata (UG4)
Theme	Study on the Synthesis of Pyrrolinones from the Reaction of Enaminones with 1,3-Dicarbonyl Compounds
Comment	She has been already starting a research work for her master thesis. Now she is getting basic organic experimental skills.


Name	Uka Sakaguchi (UG4)
Theme	Study on the Synthesis of Dumbbel-Type Molecules having Bicyclic Heterocycles at the both Ends
Comment	She believes that the dumbbell-type molecules may be some functionalities in vivo.


Name	Kouhei Tsuda (UG4)
Theme	Study on the Synthesis of Super Molecular Cage Compounds Using Manganese(III) Acetate Oxidation
Comment	He loves organic experiments using a Dimroth condenser. He is the best humorous guy in Nishino Research Group.


Name	Hideki Hayashi (UG4)
Theme	Study on the Intramolecular Cyclization of α-Hydroxyketones Using Acyl Radicals
Comment	It is difficult to learn how to use the Schlenk technique under inert gas. However, it is one of the basic organic experiment. Try to master it!


Name	Yasunobu Maemura (UG4)
Theme	Study on the Synthesis of Dibenz[b,f]oxepins
Comment	“I am a motorcycle rider having a big voice and humor. I like organic experiments as well as dinner. I am sure I become a die-hard organic chemist! Why don’t you come to join the very tough Nishino Research Group?”


Name	Kenji Yasutake (UG4)
Theme	Study on the Synthesis of Macrolides Including Naphthalenes
Comment	Be careful to do the Reformatsky reaction. Sometimes, the reaction is explosive! However, his reaction is going well at this moment. Please do his best!